Description
Zopiclone 7.5
Zopiclone 7.5 is a medication used to treat a sleeping problem called insomnia. Zopiclone is a sleeping pill that belongs to a group of drugs called non-benzodiazepine hypnotics. It has a different structure to benzodiazepine sedative hypnotics, such as Halcion (triazolam), but has similar benefits and side effects.
Zopiclone helps to reduce the amount of time it takes you to fall asleep (sleep latency), increase the amount of time you sleep for (sleep duration), and decrease the number of times you wake up at night (nocturnal awakenings). Zopiclone starts to work quickly, taking about an hour to work.
Zopiclone works by binding to a receptor in your brain called the gamma-aminobutyric acid type A (GABAA) receptor and enhancing the action of gamma-aminobutyric acid (GABA), a chemical messenger that has a calming effect.
Zopiclone became available in the 1980s and is approved for use in many parts of the world. However, it is not available in the US where it is a schedule IV controlled substance. The US Food and Drug Administration (FDA) has approved eszopiclone (Lunesta). Eszopiclone is a stereoisomer of zopiclone, which means it is made up of the same parts connected in the same sequences, but its 3D structure is different.
Zopiclone usually comes as a tablet. In some countries, your doctor may be able to order you an oral solution containing this medication if you have trouble swallowing. Branded and generic versions of zopiclone are available.
What is zopiclone used for?
Zopiclone is used for the short-term (7-14 days) treatment of insomnia in adults. It is used to treat adults who have sleep problems such as:
- Difficulty falling asleep
- Waking in the middle of the night
- Waking too early
- Severe or upsetting sleep problems that are caused by mood or mental health problems
Zopiclone is not recommended for long-term use (more than 4 weeks) for chronic insomnia because it may cause tolerance and dependence, leading to withdrawal and rebound insomnia if this medication is stopped suddenly. Long-term use is usually considered an “off-label” or unapproved use of the drug.
Important information of zopiclone 7.5
Zopiclone may cause serious side effects.
- Use of this medication may lead to the development of abuse and/or physical and psychological dependence. The risk of dependence increases with dose and duration of treatment and is greater when this medication is used for more than 4 weeks, and in patients with a history of mental disorders and/or alcohol, illicit substance or drug abuse.
- Drowsiness, difficulties breathing, coma and death may occur if zopiclone is taken together with opioids. Zopiclone and opioids should only be used at the same time, when other treatment options are inadequate. Please tell your doctor about all opioid medicines you are taking and follow your doctor’s dosage recommendations closely.
- Some studies have shown an increased risk of suicidal ideation, suicide attempt and suicide in patients taking certain sedatives and hypnotics, including this medicine. However, it has not been established whether this is caused by the medicine or if there may be other reasons. If you have suicidal thoughts, contact your doctor as soon as possible for further medical advice.
- Before taking zopiclone, it is important to make sure that you can have at least 7 to 8 hours of uninterrupted sleep to help reduce the risk of some side effects.
- Zopiclone may cause sleepwalking or other unusual behavior (such as driving, eating, making a phone call, or having sex etc.) while not being fully awake. The next morning, you may not remember that you did anything during the night. These activities may occur whether or not you drink alcohol or take other medicines that make you drowsy with zopiclone. If you experience any of the above, stop the treatment with this medication immediately and contact your doctor or healthcare provider.
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